Role of Peroxisome Proliferator-Activated Receptors in Inflammation Control
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چکیده
منابع مشابه
Role of Peroxisome Proliferator-Activated Receptors in Inflammation Control
Peroxisome proliferator-activated receptors (PPARs) were discovered over a decade ago, and were classified as orphan members of the nuclear receptor superfamily. To date, three PPAR subtypes have been discovered and characterized (PPAR $\alpha$, $\beta/\delta$, $\gamma$ ). Different PPAR subtypes have been shown to play crucial roles in important diseases and conditions such as obesity, diabete...
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Peroxisome proliferator-activated receptors (PPARs) are members of the ligand-activated nuclear hormone receptor superfamily of transcription factors that includes receptors for steroids, thyroid hormone, retinoic acid, and vitamin D. Upon activation in the cytoplasm, PPARs heterodimerize with retinoid X receptors (RXR) and form a complex that translocates to the nucleus and regulates gene expr...
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ژورنال
عنوان ژورنال: Journal of Biomedicine and Biotechnology
سال: 2004
ISSN: 1110-7243,1110-7251
DOI: 10.1155/s1110724304308065